Desenvolvimento de um ecoprocesso para obtenção de sistemas nanofibrosos, a partir da valorização de subprodutos do leite, para aplicações biomédicas

Results & Impact

This PhD project promotes the valorisation of dairy by-products from the Azores through the development of a sustainable eco-process for obtaining active biomolecules with biomedical applications. The main expected outcome is the creation of innovative hybrid systems, composed of casein-based hydrogels reinforced with nanofibres, designed for the treatment of chronic wounds. These structures mimic the extracellular matrix, providing a favourable environment for tissue regeneration.

The project is expected to have a significant scientific and technological impact by exploring ecological and sustainable methodologies for the extraction of casein and growth factors, employing microbial consortia and natural acidification processes. Simultaneously, it will strengthen knowledge in the field of biomaterials, applying advanced techniques for the characterisation and development of nanofibrous systems. From a biomedical perspective, the developed solutions aim to address a relevant public health challenge in the region — the high incidence of diabetes and associated chronic wounds — by proposing more effective and accessible therapeutic alternatives.

In addition to generating high-quality scientific knowledge, the project will contribute to the circular economy and regional sustainability by creating new opportunities for the valorization of dairy industry surpluses. The project also anticipates results with strong potential for industrial transfer, particularly the development of advanced wound dressings for clinical application. Ultimately, the project reinforces the connection between science, technology, and regional development, consolidating the research capacity of the University of the Azores and the local industrial sector.